Lope III Ximénez de Urrea y de Bardaixi, Viceroy of Sicily, fought during the Italian Wars and was involved in the Conquest of Naples, Italy. His first marriage was to Beatriz Ruiz de Liori. He later married Catalina de Centelles y de Cabrera. They had two children:
1) Beatriz Ximenez de Urrea y de Centelles married Francisco Gilabert de Centelles y Queralt, her cousin.
2) Lope IV Ximénez de Urrea y de Centelles, 1st Count of Aranda.